A complete list of Dr. Sahai’s publication by ResearchGate:


Peer-Reviewed Publications By Subject-Area:

Origins and Early Evolution of Life

  1. Sahai N. and Kaddour H. (in prep., INVITED) Editors for special thematic issue of Elements on the Orgins of Life.
  2. Sahai N. and Schoonen M. A. A. (in prep.) Geochemical constraints on the “phosphate problem” in the origins of life. For submission to Nature.
  3. Sahai N., Dalai P., Estrada C., Kaddour H., and Bass, G. (in prep.) Mineral surface effects on stability and formation rates of model protocell membranes. For submission to Life. Evol. Biosph.
  4. Kaddour H. and Sahai N. (in prep.) Potential synergism and mutualism in the origins of life: A one-pot experimental approach to non-enzymatic polymerization of RNA and peptides.
  5. Kaddour H. and Sahai N. (2014) Nonenzymatic polymerization of RNA: advances and challenges. INVITED for special issue of Life 4, 598-620.
  6. Greiner E., Kumar K., Sumit M., Giuffre A., Zhao W., Pedersen J. and Sahai N. (2014) Adsorption of L-glutamate and L-aspartate from solution to g-Al2O3. Geochim. Acta 133, 142-155.
  7. Xu J., Sahai N., Eggleston C. M. and Schoonen M. A. A. (2013) Reactive oxygen species at the oxide/water interface: Formation mechanisms and implications for prebiotic chemistry and the origin of life. Planet. Sci. Lett. 363, 156-167.
  8. Xu J., Campbell J., Zhang N., Hickey W. J. and Sahai N. (2012) Evolution of bacterial biofilms as armor against mineral toxicity. Astrobiology 12, 785-798.
  9. Cleaves H. J. III, Scott A. M., Hill F. C., Leszczynsky J., Sahai N. and Hazen R. (2012) Mineral-organic interfacial processes: potential roles in the origin of life. Soc. Rev. 41, 5365-5568. INVITED.
  10. Oleson T. A., Wesolowski D. J., Dura J. A., Majkrzak C. F., Giuffre A. J. and Sahai N. (2012) Neutron reflectvity study of phosphatidylcholine bilayers on sapphire (110). Colloid. Interf. Sci. 370,192-200.
  11. Oleson T. A. and Sahai N. (2010) Interaction energies between oxide surfaces and multiple phosphatidylcholine bilayers from extended DLVO-theory. Colloid. Interf. Sci. 352, 316-326.
  12. Oleson T. A., Sahai N. and Pedersen J. A. (2010) Electrostatic effects on deposition of multiple phospholipid bilayers at oxide surfaces. Colloid. Interf. Sci. 352, 327-336.
  13. Xu J., Stevens M. J., Oleson T. A., Last J. A. and Sahai N. (2009) Role of oxide surface chemistry and phospholipid phase on adsorption and self-assembly: isotherms and atomic force microscopy. Phys. Chem. C 113, 2187-2196. Special issue on Physical Chemistry of Environmental Interfaces. INVITED.
  14. Oleson T. A. and Sahai N. (2008) Oxide-dependent adsorption and self-assembly of dipalymitoylphosphatidylcholine, a cell-membrane phospholipid: Bulk Adsorption Isotherms. Langmuir 24, 4865-4873.
  15. Sahai N. (2002a) Biomembrane phospholipid-oxide surface interactions: crystal chemical and thermodynamic basis. Colloid. Interf. Sci. 252, 309-319.


Bone Biomineralization and Silicate Biomaterials

  1. Wang Z., Xu Z., Zhao W. and Sahai N. (in prep.) The mechanism of citrate in controlling hydroxyapatite nanocrystal growth: an integrated experimental and computational study. For submission to Langmuir.
  2. Wang Z., Zhao W., Xu X. and Sahai N. (in review) A potential mechanism for amino acid-controlled crystal growth of hydroxyapatite.
  3. Xu Z., Zhao W., Wang Z., Cui Q. and Sahai N. (in prep.) Detailed structure analysis of collagen fibrils in distinguishing mechanisms for intrafibrillar collagen mineralization in skeletal tissues. For submission to Nat. Acad. Sci.
  4. Zhou X., Zhang N. and Sahai N. (in prep.) Silicates in orthopaedic and bone tissue engineering materials. For submission to Tissue Eng. Part B.
  5. Zhou X., Zhang N., Moussa F., Molenda J., Safadi F., Murphy W. and Sahai N. (in review) Soluble silicate stimulates osteogenic differentiation and suppresses osteoclastic differentiation by antagonizing NF-κB activation via miR-146a: implications for bone remodeling.
  6. Zhou X. and Sahai N. (2015) Biomimetic and Nanostructured Hybrid Bioactive Glass. Biomaterials. DOI: 10.1016/j.biomaterials.2015.01.024.
  7. Zhao W. and Sahai N. (2015, accepted) Organic-Mineral Interactions in Biomineralization. INVITED chapter, Molecular Modeling of Geochemical Reactions: An Introduction, Ed. J. Kubicki, John Wiley.
  8. Xu Z., Yang Y., Zhao W., Wang Z., Landis W. J., Cui Q. and Sahai N. (2015) Molecular mechanisms for intrafibrillar collagen mineralization in skeletal tissues. Biomaterials 39, 59-66.
  9. Xu Z., Yang Y., Cui Q. and Sahai N. (2014) Small biomolecule-mediated hydroxyapatite growth: free energy calculations benchmarked to density functional theory. Comput. Chem. 35, 70-81.
  10. Zhao W., Xu Z., Yang Y. and Sahai N. (2014) Surface energetics of the hydroxyapatite-water interface: a molecular dynamics study. Langmuir 30, 13283-13292.
  11. Yang Y., Xu Z., Cui Q. and Sahai N. (2014) Molecular simulation of biomineral nucleation and crystal growth: Modern computational challenges and approaches. INVITED chapter in Biomineralization Sourcebook: Characterization of Biominerals and Biomimetic Materials, Chapter 17, Eds. E. DiMasi and L. Gower, CRC Press, Boca Raton, FL.
  12. Chapron Y., Charlet L. and Sahai N. (2014) Fate of pathological prion (PrPsc 92-138) in soil and water: prion-clay nanoparticle molecular dynamics. Biomol. Struct. Dynam. 32, 1802-1816.
  13. Zhang N., Molenda J., Murphy W. and Sahai N. (2013) Crystal structure control of CaSiO3 bioceramics on human mesenchymal stem cell attachment, proliferation and differentiation into osteoblasts. Sci. 1, 1101-1110..
  14. Yang Y., Mkhonto D., Cui Q. and Sahai N. (2011) Theoretical study of bone sialoprotein in hydroxyapatite biomineralization. Special Issue of Cells Tissues Organs 194, 182-197.
  15. Yang Y., Cui Q. and Sahai N. (2010) How does bone sialoprotein promote the nucleation of hydroxyapatite? A molecular dynamics study using model peptides of different conformations. Langmuir 26, 9848- 9859.
  16. Zhang N., Molenda J., Fournelle J., Murphy W. and Sahai N. (2010) Effects of pseudowollastonite (b-CaSiO3) on human mesenchymal stem cell activity. Biomaterials 31, 7653-7665.
  17. Stevens M. J., Donato L.J., Lower S. K., and Sahai N. (2009) Oxide-dependent adhesion of the Jurkat cell line of T-lymphocytes. Langmuir 25, 6270-6278.
  18. Sahai N. (2007) Medical Mineralogy and Geochemistry: An Interfacial Science. Elements 3, 383-386. Editor, N. Sahai.
  19. Sahai N., Schoonen M., and Skinner H. C. W. (2006) The emerging field of medical mineralogy and geochemistry. INVITED, reviewed chapter for Medical Mineralogy and Geochemistry, Eds. Nita Sahai and Martin Schoonen, Reviews in Mineralogy and Geochemistry Series, Vol. 64, Mineralogical Society of America, Washington, D.C., Chapter 1.
  20. Cerruti M. and Sahai N. (2006) Silicate biomaterials for orthopaedic and dental implants. INVITED, reviewed chapter for Medical Mineralogy and Geochemistry, Eds. Nita Sahai and Martin Schoonen, Reviews in Mineralogy and Geochemistry Series, Vol. 64, Mineralogical Society of America, Washington, D.C., Chapter 9.
  21. Sahai N. (2005) Modeling apatite nucleation in the human body and in the geochemical environment, J. Sci. INVITED, for special issue of Am. J. Sci. 305, 661-672.
  22. Sahai N. and Anseau M. (2005) Cyclic silicate active site and epitaxial apatite nucleation on pseudowollastonite bioceramic-bone interfaces. Biomaterials 26, 5763-5370.
  23. Anseau M. R., Leung P., Sahai N. and Swaddle, T. W. (2005) Interactions of silicate ions with zinc(II) and aluminum(III) in alkaline aqueous solution. Chem. 44, 8023-8032.
  24. Sahai N. (2003a) The effects of Mg2+ and H+ on nucleation of authigenic apatite at silica surfaces. Cosmochim. Acta 67, 1017-1030, INVITED.
  25. Sahai N. and Tossell J. A. (2000) Molecular orbital study of apatite nucleation at silica bioceramic surfaces. Phys. Chem. B. 104, 4322-4341.


Carbonate and Silica Biomineralization

  1. Yang Y., Sahai N., Romanek C. and Chakraborty S. (2012) Low-temperature dolomite (Ca, Mg(CO3)2) formation as a potential biosignature– A computational study of Mg2+ dehydration in aqueous solution in the presence of inorganic anions. Cosmochim. Acta 88, 77-87.
  2. Romanek C. S., Jiménez-López , Rodriguez Navarro A., Sánchez-Román M., Sahai N. and Coleman M. (2009) Inorganic synthesis of Fe-Ca-Mg carbonates at low temperature. Geochim. Cosmochim. Acta 73, 5361-5376.
  3. Delak K. M. and Sahai N. (2006) Investigations into the mechanisms of amine-catalyzed hydrolysis of organosilicates. Phys. Chem. B. 110, 17819-17829.
  4. Delak K. M. and Sahai N. (2005) Amine-catalyzed biomimetic hydrolysis and polymerization of organosilicate. Mater. 17, 3221-3227.
  5. Delak K. M., Farrar T. C. and Sahai N. (2005) 29Si NMR sensitivity enhancement methods for the quantitative study of organosilicate hydrolysis and condensation. Non-Cryst. Solids 351, 2244-2250.
  6. Sahai N. (2004) Calculation of 29Si NMR shifts of silicate complexes with carbohydrates, amino-acids and carboxylic acids: Potential role in biological silica utilization. Cosmochim. Acta 68 227-238.
  7. Sahai N. (2003b) Silicon-organic interactions in the environment and in organisms. INVITED, reviewed chapter in Geochemical and Hydrological Reactivity of Heavy Metals in Soils, W. L. Kingery and H. M. Selim, Chapter 6. CRC Press, Boca Raton, FL.
  8. Sahai N. and Tossell J. A. (2002) 29Si NMR shifts and relative stabilities calculated for aqueous hypervalent silicon-polyalcohol complexes: role in sol-gel and biogenic silica synthesis. Chem. 41, 748-756.
  9. Sahai N. and Tossell J. A. (2001) Formation energies and NMR chemical shifts calculated for putative serine-silicate complexes in silica biomineralization. Cosmochim. Acta 65, 2043-2053.


Environmental Geochemistry

  1. Hochella M. F., Jr., Lower S. K., Maurice P. A., Penn R. L., Sahai N., Sparks D. L. and Twining B. S. (2008) Nanominerals, mineral nanoparticles, and Earth systems. Science 319, 1631-1635.
  2. Ciardelli M. C., Xu H. and Sahai N. (2008) Role of Fe(II), phosphate, silicate, sulfate and carbonate in arsenic uptake by coprecipitation in synthetic and natural groundwater. Water Res. 42, 615-624.
  3. Sahai N., Lee Y., Xu H., Ciardelli M. C. and Gaillard J.-F. (2007) Role of Fe(II) and phosphate in arsenic uptake by coprecipitation. Cosmochim. Acta 71, 3193-3210.
  4. Sahai N. and Rosso K. (2006) Linking molecular modeling to surface complexation modeling. INVITED, reviewed chapter for Surface Complexation Modelling, Ed. Johannes Lutzenkirchen, Interface Science and Technology Series, Vol. 11, Elsevier, Amsterdam.
  5. Thornburg K. and Sahai N. (2004) Arsenic occurrence, mobility, and retardation in sandstone and dolomite formations of the Fox River Valley, Wisconsin. Sci. Technol. 38, 5087-5094.
  6. Sahai N. (2002b) Is silica really an anomalous oxide? Aqueous hydrolysis and surface acidity revisited. Sci. Technol. 36, 445-452.
  7. Tossell J. A. and Sahai N. (2000) Calculating the acidity of silanols and related oxyacids in aqueous solution. Cosmochim. Acta 64, 4097-4113.
  8. Sahai N. (2000) Estimating adsorption enthalpies and affinity sequences of monovalent electrolyte ions on oxide surfaces in aqueous solution. Cosmochim. Acta 64, 3629-3641.
  9. O’ Day P.A., Newville M., Neuhoff P., Sahai N. and Carroll S. A. (2000) X-Ray absorption spectroscopy of strontium (II) coordination: I. static and thermal disorder in crystalline, hydrated and precipitated solids and in aqueous solution. Colloid. Interface Sci. 222, 184-197.
  10. Sahai N., Carroll S. A., O’ Day P. A. and Roberts S. (2000) X-Ray absorption spectroscopy of strontium (II) coordination: II. Sorption and precipitation at kaolinite, amorphous silica and goethite surfaces. Colloid. Interface Sci. 222, 198-212.
  11. Koretsky C. M., Sverjensky D. A. and Sahai N. (1998) Calculating site densities of oxides and silicates from crystal structures. J. Sci. 298, 349-38.
  12. Sverjensky D. A. and Sahai N.(1998) Prediction of surface-protonation enthalpies for oxides. Cosmochim. Acta 62, 3703-3715.
  13. Sahai N. and Sverjensky D. A. (1998) GEOSURF: A computer program for modeling adsorption on mineral surfaces in solution. Geosci. 24, 853-873.
  14. Sahai N. and Sverjensky D. A. (1997a) Evaluation of internally-consistent parameters for the triple-layer model by the systematic analysis of oxide surface titration data, Cosmochim. Acta 61, 2801-2826.
  15. Sahai N. and Sverjensky D. A. (1997b) Solvation and electrostatic model for specific electrolyte adsorption. Cosmochim. Acta 61, 2827-2848.
  16. Sverjensky D. A. and Sahai N. (1996) Theoretical prediction of single-site surface protonation equilibrium constants for oxides and silicates in water. Cosmochim. Acta 60, 3773-3797.


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